Bioinformatic mapping of AlkB homology domains in viruses

Bioinformatic mapping and production of recombinant N-terminal domains of human cardiac ryanodine receptor 2

We report the domain analysis of the N-terminal region (residues 1-759) of the human cardiac ryanodine receptor (RyR2) that encompasses one of the discrete RyR2 mutation clusters associated with catecholaminergic polymorphic ventricular tachycardia (CPVT1) and arrhythmogenic right ventricular dysplasia (ARVD2). Our strategy utilizes a bioinformatics approach complemented by protein expression, ...

Cyclic Homology of Dedekind Domains

The purpose of this paper is to calculate the cyclic homology of rings of integers of global fields. We accomplish this by explicitly computing the homology of the simple complex associated to Tsygan’s double complex. To accomplish this, we first compute the cyclic homology of cyclic algebras, i.e., algebras of the form A = R[t]/(P (t)), where P is a monic polynomial with coefficients in R. Mor...

stability and attraction domains of traffic equilibria in day-to-day dynamical system formulation

در این پژوهش مسئله واگذاری ترافیک را از دید سیستم های دینامیکی فرمول بندی می کنیم.فرض کرده ایم که همه فاکتورهای وابسته در طول زمان ثابت باشند و تعادل کاربر را از طریق فرایند منظم روزبه روز پیگیری کنیم.دینامیک ترافیک توسط یک نگاشت بازگشتی نشان داده می شود که تکامل سیستم در طول زمان را نشان می دهد.پایداری تعادل و دامنه جذب را توسط مطالعه ویژگی های توپولوژیکی تکامل سیستم تجزیه و تحلیل می کنیم.پاید...

Pleckstrin Homology Domains in Cell Signaling

Single calponin homology domains are not actin-binding domains

In the early 1980s, the oncogene field was in transition. The biological properties of more than 20 oncogenes had been described in animal tumor models and cell transformation assays. Attention was shifting to the question of how these genes actually function. In a few cases, it was obvious. The v-Sis protein (encoded by the transforming gene of simian sarcoma virus) was shown to be related to ...